Population Pharmacokinetics of Intravenous Salbutamol in Children with Refractory Status Asthmaticus
نویسندگان
چکیده
منابع مشابه
Soluble CD14 in children with status asthmaticus.
BACKGROUND Inflammation is a major component in the pathogenesis of asthma. CD14 is an endotoxin (lipopolysaccharide) receptor, and is expressed mainly on monocytes and macrophages. Binding of LPS to CD14 activates the monocyte or macrophage and causes the release of different cytokines. The soluble form of CD14 is present in serum, and its concentration increases in several clinical conditions...
متن کاملExperience with use of extracorporeal life support for severe refractory status asthmaticus in children
INTRODUCTION Severe status asthmaticus (SA) in children may require intubation and mechanical ventilation with a subsequent increased risk of death. In the patient with SA and refractory hypercapnoeic respiratory failure, use of extracorporeal life support (ECLS) has been anecdotally reported for carbon dioxide removal and respiratory support. We aimed to review the experience of a single paedi...
متن کامل[Management of status asthmaticus in children].
Acute bronchial asthmatic episodes represent one of the most common respiratory emergencies in medical practice. Its maximum expression "status asthmaticus", is an entity of low incidence in our medium, still it is a risk to the physical integrity of the patient. The management of an acute attack of asthma can be focused on doing away with the bronchial spasm and decreasing the inflammatory eff...
متن کاملWerner Status Asthmaticus in Children : A Review
2001;119;1913-1929 Chest Heinrich A. Werner Status Asthmaticus in Children : A Review http://chestjournal.org/cgi/content/abstract/119/6/1913 can be found online on the World Wide Web at: The online version of this article, along with updated information and services ). ISSN: 0012-3692. http://www.chestjournal.org/misc/reprints.shtml ( written permission of the copyright holder No part of this ...
متن کاملPopulation pharmacokinetics of single-dose intravenous paracetamol in children.
BACKGROUND To determine the pharmacokinetics (PK) of a new i.v. formulation of paracetamol (Perfalgan) in children ≤15 yr of age. METHODS After obtaining written informed consent, children under 16 yr of age were recruited to this study. Blood samples were obtained at 0, 15, 30 min, 1, 2, 4, 6, and 8 h after administration of a weight-dependent dose of i.v. paracetamol. Paracetamol concentrat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Pharmacokinetics
سال: 2019
ISSN: 0312-5963,1179-1926
DOI: 10.1007/s40262-019-00811-y